Korro Bio (Frequency Therapeutics) ^{Priced, Nasdaq: KRRO}

We are a clinical-stage biotechnology company focused on harnessing the body’s innate biology to repair or reverse damage caused by a broad range of degenerative diseases. Our proprietary approach, called Progenitor Cell Activation (PCA) uses combinations of small molecules to activate progenitor cells within the body to create functional tissue. Further, these progenitor cells, which are closely related to stem cells, are already resident in the targeted location in the body and programmed to develop and differentiate into specific cell types within an organ. Our initial therapeutic focus is sensorineural hearing loss (SNHL) and we believe our PCA platform has the potential to produce a new class of medicines and provide transformative benefits for patients across a wide range of degenerative conditions, including multiple sclerosis, or MS, and diseases of the muscle, gastrointestinal tract, skin, and bone. We intend to continue to identify areas with high unmet need where our PCA platform and novel approach to regenerative medicine could lead to potentially disease-modifying therapeutics that create healthy functional tissues and improve patients’ lives. We are developing our lead product candidate, FX-322, to treat the underlying cause of SNHL and have completed a Phase 1/2 clinical trial of FX-322 in 23 patients with stable SNHL in which we observed a statistically significant improvement in word recognition, a key measure of hearing function, and FX-322 was observed to be well tolerated.