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Lung disease biotech AN2 Therapeutics sets terms for $60 million IPO

March 21, 2022
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AN2 Therapeutics, a Phase 2/3-ready biotech developing an in-licensed therapy for NTM lung disease, announced terms for its IPO on Monday.

The Menlo Park, CA-based company plans to raise $60 million by offering 4 million shares at a price range of $14 to $16. At the midpoint of the proposed range, AN2 Therapeutics would command a fully diluted market value of $287 million.

The company's initial candidate is epetraborole, a once-daily oral treatment for patients with chronic non-tuberculous mycobacterial (NTM) lung disease. The company in-licensed the exclusive worldwide development and commercialization rights for epetraborole from Anacor Pharmaceuticals (acquired by Pfizer) in 2016. AN2 Therapeutics plans to conduct a Phase 2/3 trial in treatment-refractory Mycobacterium avium complex lung disease, which is the most common type of NTM lung disease. The trial design is currently under review from the FDA, and the company plans to initiate enrollment in the 1H22, with topline results for the Phase 2 part expected in mid-2023.

AN2 Therapeutics was founded in 2017 and plans to list on the Nasdaq under the symbol ANTX. Cowen, SVB Leerink, and Evercore ISI are the joint bookrunners on the deal. It is expected to price during the week of March 21, 2022.