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Brain disease biotech Neumora Therapeutics sets terms for $250 million IPO

September 11, 2023
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Neumora Therapeutics, a Phase 3 biotech developing therapies for brain diseases, announced terms for its IPO on Monday.

The Watertown, MA-based company plans to raise $250 million by offering 14.7 million shares at a price range of $16 to $18. At the midpoint of the proposed range, Neumora Therapeutics would command a fully diluted market value of $2.8 billion.

The company's pipeline consists of seven clinical and preclinical neuroscience programs that target novel mechanisms of action for a broad range of underserved neuropsychiatric disorders and neurodegenerative diseases. Its lead candidate, navacaprant (NMRA-140), is a novel once-daily oral kappa opioid receptor (KOR) antagonist that is being developed for the treatment of major depressive disorder (MDD), which the company believes has the potential to provide significant advantages relative to the standard of care, if approved. Neumora is initiating a pivotal Phase 3 program for navacaprant monotherapy in patients with moderate to severe MDD and anticipates releasing topline results for the first of three efficacy studies in the 2H24.

Neumora Therapeutics was founded in 2019 and plans to list on the Nasdaq under the symbol NMRA. J.P. Morgan, BofA Securities, Stifel, Guggenheim Securities, RBC Capital Markets, and William Blair are the joint bookrunners on the deal. It is expected to price during the week of September 11, 2023.